New pieces added to the molecular puzzle of rheumatoid arthritis

(Walter and Eliza Hall Institute) researchers have revealed new details about how joint inflammation evolves in rheumatoid arthritis, and the cells that prolong the inflammatory attack.The team pinpointed an unexpected source of the inflammatory protein GM-CSF in rheumatoid arthritis, and explained how GM-CSF signals to prolong joint inflammation.These discoveries could indicate potential new therapeutic targets for reducing joint inflammation in rheumatoid arthritis, and could potentially reduc...